Blood Transfusion Services

This section outlines the payment policy and claims filing instructions for blood transfusions and related services.

Introduction

Payment Policy

Payment for blood transfusion services is HMSA's eligible charge less any member copayment and/or deductible.

HMSA's payment for blood transfusion services is an all-inclusive rate that includes, but is not limited to, blood processing and storage, transfusion medicine services, professional services (including nonphysician services), use of the treatment and/or recovery room, associated medical/surgical supplies, and routine and oral pharmacy items.

Note: The all-inclusive rate can be billed for each day that an HMSA member receives blood transfusion services.

Coding

Using the correct combination of codes is the key to minimizing delays in claims processing. Please ensure that revenue codes and procedure codes reflect the diagnoses and services rendered. Third-digit subcategories for the revenue code are included in the UB-04 manual.

Commonly Billed Services

The matrix below depicts commonly billed services and acceptable code ranges that correspond to HMSA's claims processing requirements for blood transfusion services. The matrix represents a range of possible combinations and should not be viewed as comprehensive.

Administration

Revenue CodeDescriptionLevel of CodeCodeDescription
0391Blood administration (e.g., transfusion)CPT36430Transfusion, blood or blood components
71xRecovery room   
76xSpecialty room - Treatment/observation room  Although recommended by Medicare's ambulatory payment classification (APC), this code is part of HMSA's all-inclusive rate and is not paid separately

Incidental Drugs and Supplies

Incidental drugs and supplies are used to deliver the service. These items are included in the administration fee and are not reimbursed separately.

Revenue CodeDescriptionLevel of CodeCodeDescription
25xPharmacyHCPCS Use HCPCS codes that describe the services rendered.
27xMedical/surgical supplies and devicesHCPCS Use HCPCS codes that describe the services rendered.
30xLaboratoryCPT86850 - 86999Immunology and transfusion medicine services such as antibody screens, blood typing and blood preparation.

Blood and Blood Products Requiring Specific Identification

Blood and blood products requiring specific identification must be billed separately. Refer to Payment Policies – Enhanced Code Editing for additional billing guidance under Blood and Blood Product Charges.

Revenue CodeDescriptionLevel of CodeCodeDescription
0380 - 0389Blood and blood productsHCPCSP90XXBlood – Use HCPCS codes that describe the services rendered

Blood Processing and Storage

Refer to Payment Policies – Enhanced Code Editing for additional billing guidance under Blood Processing and Storage Charges.

Revenue CodeDescriptionLevel of CodeCodeDescription
0390 - 0399Blood storage and processingHCPCSP90XXBlood – Use HCPCS codes that describe the services rendered

Billing Tips

Blood Transfusion in an Emergency Room

CPT code 36430 (transfusion, blood or blood components) may be billed as a separate line item when the service is performed in conjunction with an emergency room visit.

Laboratory Services

Laboratory services for blood transfusion are considered part of the all-inclusive rate. This holds true even if the blood work is done the day before the actual transfusion.

Treatment Room

Any treatment and/or recovery room used in conjunction with blood transfusion services is part of the all-inclusive rate and should not be billed separately.

Other Services

The following services are not included in the all-inclusive rate for blood transfusions and must be billed separately: chemotherapy, laboratory/pathology, radiology, radiotherapy, diagnostic tests and patient convenience items.

Service Units

Blood transfusion services (as well as injectable drugs and other therapeutic services) must be billed as one unit. The number of units in form locator 46 should never be greater than one per line item when billing revenue code 391.


Revision History

Date Nature of Revision
10/01/2026
  • Updated Blood and Blood Products Requiring Specific Identification table to add P90XX and remove P9010, P9011, P9012, P9016, P9017, P9019, P9020, P9021, P9022, P9023, P9031, P9040, P9044
  • Added Blood Processing and Storage table
  • Removed UB 04 Highlights: Sample Claim section including Explanation of Sample Claim table
09/28/2026

Migrated to new platform.